What is an example of a Type E ADR?

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Multiple Choice

What is an example of a Type E ADR?

Explanation:
Type E adverse drug reactions are withdrawal syndromes that occur after stopping a drug the body has become physiologically dependent on. They happen because repeated exposure causes adaptive changes in the body, and removing the drug unmasks these adaptations, producing symptoms often opposite to the drug's effects. Opiate withdrawal is a classic example: after prolonged opioid use, stopping the drug can lead to symptoms like sweating, runny nose, yawning, muscle aches, and GI upset. This illustrates the withdrawal phenomenon central to Type E ADRs. Other options aren’t as fitting because they’re either too nonspecific (withdrawal reaction), not a defined ADR category (end of use), or unrelated to withdrawal phenomena (resistance to antimicrobial agents).

Type E adverse drug reactions are withdrawal syndromes that occur after stopping a drug the body has become physiologically dependent on. They happen because repeated exposure causes adaptive changes in the body, and removing the drug unmasks these adaptations, producing symptoms often opposite to the drug's effects.

Opiate withdrawal is a classic example: after prolonged opioid use, stopping the drug can lead to symptoms like sweating, runny nose, yawning, muscle aches, and GI upset. This illustrates the withdrawal phenomenon central to Type E ADRs.

Other options aren’t as fitting because they’re either too nonspecific (withdrawal reaction), not a defined ADR category (end of use), or unrelated to withdrawal phenomena (resistance to antimicrobial agents).

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