Type A adverse drug reactions are usually dose-dependent and predictable.

• A. False
• B. True
• C. Sometimes true
• D. Not enough data

Answer: (B)

Type A adverse drug reactions are augmented pharmacologic effects; they arise from the drug’s known mechanism and scale with drug intensity. Because they reflect the body's response to the drug concentration, these reactions are dose-dependent and predictable, meaning higher doses increase both likelihood and severity. This predictability allows management by dose adjustment, slower titration, or stopping the drug. Typical examples include hypoglycemia from insulin or bleeding with anticoagulants, where the reaction mirrors the drug’s pharmacology. In contrast, other reaction types are not dose-related and can be unpredictable, so the statement here correctly describes Type A ADRs as usually dose-dependent and predictable.