An example of biological variability in racial differences involves differences in ethanol metabolism most notably in which population?

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Multiple Choice

An example of biological variability in racial differences involves differences in ethanol metabolism most notably in which population?

Explanation:
Genetic differences in how ethanol is processed illustrate novel metabolic variability, especially due to ALDH2 deficiency that is common in East Asian populations. Alcohol is first converted to acetaldehyde by ADH, then acetaldehyde is cleared to acetate by aldehyde dehydrogenase (ALDH2). When ALDH2 is inactive, acetaldehyde lingers after drinking, causing flushing, rapid heart rate, nausea, and other unpleasant effects. This prominent impairment in ethanol metabolism among Asians makes this population the best example of biological variability in racial differences for ethanol processing.

Genetic differences in how ethanol is processed illustrate novel metabolic variability, especially due to ALDH2 deficiency that is common in East Asian populations. Alcohol is first converted to acetaldehyde by ADH, then acetaldehyde is cleared to acetate by aldehyde dehydrogenase (ALDH2). When ALDH2 is inactive, acetaldehyde lingers after drinking, causing flushing, rapid heart rate, nausea, and other unpleasant effects. This prominent impairment in ethanol metabolism among Asians makes this population the best example of biological variability in racial differences for ethanol processing.

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